Nef Secretion into Extracellular Vesicles or Exosomes Is Conserved across Human and Simian Immunodeficiency Viruses

Extracellular vesicles (EVs) or exosomes have been implicated in the pathophysiology of infections and cancer. The negative regulatory factor (Nef) encoded by simian immunodeficiency virus (SIV) and human immunodeficiency virus (HIV) plays a critical role in the progression to AIDS and impairs endos...

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Библиографические подробности
Опубликовано в: :mBio
Главные авторы: McNamara, Ryan P., Costantini, Lindsey M., Myers, T. Alix, Schouest, Blake, Maness, Nicholas J., Griffith, Jack D., Damania, Blossom A., MacLean, Andrew G., Dittmer, Dirk P.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2018
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801467/
https://ncbi.nlm.nih.gov/pubmed/29437924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02344-17
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