Nef Secretion into Extracellular Vesicles or Exosomes Is Conserved across Human and Simian Immunodeficiency Viruses

Extracellular vesicles (EVs) or exosomes have been implicated in the pathophysiology of infections and cancer. The negative regulatory factor (Nef) encoded by simian immunodeficiency virus (SIV) and human immunodeficiency virus (HIV) plays a critical role in the progression to AIDS and impairs endos...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: McNamara, Ryan P., Costantini, Lindsey M., Myers, T. Alix, Schouest, Blake, Maness, Nicholas J., Griffith, Jack D., Damania, Blossom A., MacLean, Andrew G., Dittmer, Dirk P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801467/
https://ncbi.nlm.nih.gov/pubmed/29437924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02344-17
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