Maintenance of AP-2-Dependent Functional Activities of Nef Restricts Pathways of Immune Escape from CD8 T Lymphocyte Responses

Nef-specific CD8(+) T lymphocytes (CD8TL) are linked to extraordinary control of primate lentiviral replication, but the mechanisms underlying their efficacy remain largely unknown. The immunodominant, Mamu-B*017:01(+)-restricted Nef(195-203)MW9 epitope in SIVmac239 partially overlaps a sorting moti...

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Veröffentlicht in:J Virol
Hauptverfasser: Schouest, Blake, Weiler, Andrea M., Janaka, Sanath Kumar, Myers, Tereance A., Das, Arpita, Wilder, Sarah C., Furlott, Jessica, Baddoo, Melody, Flemington, Erik K., Rakasz, Eva G., Evans, David T., Friedrich, Thomas C., Maness, Nicholas J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
Schlagworte:
Cellular Response to Infection
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809740/
https://ncbi.nlm.nih.gov/pubmed/29237831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01822-17
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