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Expression and Functional Characterization of Two Natural Heparin-binding Site Variants of Antithrombin

BACKGROUND: Several heparin-binding site (HBS) variants of antithrombin (AT) have been identified which predispose carriers to higher incidence of thrombosis. The cause of thrombosis in carriers of HBS variants has been primarily attributed to a loss in their heparin-dependent anticoagulant function...

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Bibliografische gegevens
Gepubliceerd in:J Thromb Haemost
Hoofdauteurs: Dinarvand, Peyman, Yang, Likui, Villoutreix, Bruno O., Rezaie, Alireza R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809256/
https://ncbi.nlm.nih.gov/pubmed/29215785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13920
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