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Expression and Functional Characterization of Two Natural Heparin-binding Site Variants of Antithrombin

BACKGROUND: Several heparin-binding site (HBS) variants of antithrombin (AT) have been identified which predispose carriers to higher incidence of thrombosis. The cause of thrombosis in carriers of HBS variants has been primarily attributed to a loss in their heparin-dependent anticoagulant function...

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Publicat a:J Thromb Haemost
Autors principals: Dinarvand, Peyman, Yang, Likui, Villoutreix, Bruno O., Rezaie, Alireza R.
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809256/
https://ncbi.nlm.nih.gov/pubmed/29215785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13920
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