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Expression and Functional Characterization of Two Natural Heparin-binding Site Variants of Antithrombin
BACKGROUND: Several heparin-binding site (HBS) variants of antithrombin (AT) have been identified which predispose carriers to higher incidence of thrombosis. The cause of thrombosis in carriers of HBS variants has been primarily attributed to a loss in their heparin-dependent anticoagulant function...
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| Publicado no: | J Thromb Haemost |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5809256/ https://ncbi.nlm.nih.gov/pubmed/29215785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13920 |
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