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CD40 Mediates Maturation of Thymic Dendritic Cells Driven by Self-reactive CD4(+) Thymocytes and Supports Development of Natural Regulatory T Cells

Thymic dendritic cells (tDCs) play an important role in central tolerance by eliminating self-reactive thymocytes or differentiating them to regulatory T (Treg) cells. However, the molecular and cellular mechanisms underlying these functions are not completely understood. We found that mouse tDCs un...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Immunol
Egile Nagusiak: Oh, Jaehak, Wu, Nan, Barczak, Andrea J., Barbeau, Rebecca, Erle, David J., Shin, Jeoung-Sook
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809249/
https://ncbi.nlm.nih.gov/pubmed/29321275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700768
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