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Antigen-specific thymocyte feedback regulates homeostatic thymic conventional dendritic cell maturation

Thymic dendritic cells (DC) mediate self-tolerance by presenting self-peptides to and depleting autoreactive thymocytes. Despite a significant role in negative selection, the events regulating thymic DC maturation and function under steady-state conditions are poorly understood. We report that cross...

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Detalhes bibliográficos
Main Authors: Spidale, Nicholas A., Wang, Bo, Tisch, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4114159/
https://ncbi.nlm.nih.gov/pubmed/24890722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400321
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