लोड हो रहा है...
De novo glucocorticoid synthesis by thymic epithelial cells regulates antigen-specific thymocyte selection
Glucocorticoid (GC) signaling in thymocytes counters negative selection and promotes the generation of a self-tolerant yet antigen-responsive T-cell repertoire. Whereas circulating GC are derived from the adrenals, GC are also synthesized de novo in the thymus. The significance of this local product...
में बचाया:
| में प्रकाशित: | J Immunol |
|---|---|
| मुख्य लेखकों: | , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2018
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5840004/ https://ncbi.nlm.nih.gov/pubmed/29440508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1701328 |
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