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Thymocyte responsiveness to endogenous glucocorticoids is required for immunological fitness
Generation of a self-tolerant but antigen-responsive T cell repertoire occurs in the thymus. Although glucocorticoids are usually considered immunosuppressive, there is also evidence that they play a positive role in thymocyte selection. To address the question of how endogenous glucocorticoids migh...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3386828/ https://ncbi.nlm.nih.gov/pubmed/22653054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI63067 |
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