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Thymic dendritic cell subsets display distinct efficiencies and mechanisms of intercellular MHC transfer
Thymic dendritic cells (DC) delete self-Ag-specific thymocytes, and drive development of FoxP3-expressing immunoregulatory T cells. Unlike medullary thymic epithelial cells (mTEC), which express and present peripheral self-Ag, DC must acquire self-Ag to mediate thymic negative selection. One such me...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5173434/ https://ncbi.nlm.nih.gov/pubmed/27895179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601516 |
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