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Intercellular Protein Transfer from Thymocytes to Thymic Epithelial Cells

Promiscuous expression of tissue restricted antigens (TRAs) in medullary thymic epithelial cells (mTECs) is crucial for negative selection of self-reactive T cells to establish central tolerance. Intercellular transfer of self-peptide-MHC complexes from mTECs to thymic dendritic cells (DCs) allows D...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wang, Hong-Xia, Qiu, Yu-Rong, Zhong, Xiao-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4811443/
https://ncbi.nlm.nih.gov/pubmed/27022746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0152641
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