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Strain specific maturation of Dendritic cells and production of IL-1β controls CD40-driven colitis
Intestinal integrity is maintained by balanced numbers of CD103(+) Dendritic cells (DCs), which generate peripherally induced regulatory T cells (iTregs). We have developed a mouse model where DC-specific constitutive CD40 signals caused a strong reduction of CD103(+) DCs in the lamina propria (LP)...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6336277/ https://ncbi.nlm.nih.gov/pubmed/30653608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210998 |
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