Adenovirus co-expressing CD40 ligand and interleukin (IL)-2 contributes to maturation of dendritic cells and production of IL-12

The aim of the present study was to construct a chimeric adenovirus (Ad)5/F35 co-expressing human CD4O ligand (CD4OL) and interleukin (IL)-2 (Ad5/F35 CD40L-IL-2). The infection efficiency to human monocyte-derived dendritic cells (Mo-DCs), expression of genes, phenotype changes and IL-12 production...

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Publicado no:Biomed Rep
Main Authors: Guo, Zhi, Gao, Hong-Yan, Zhang, Tian-Yang, Lou, Jin-Xing, Yang, Kai, Liu, Xiao-Dong, He, Xue-Peng, Chen, Hui-Ren
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5103675/
https://ncbi.nlm.nih.gov/pubmed/27882218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/br.2016.773
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