Contribution of Interleukin-12 p35 (IL-12p35) and IL-12p40 to Protective Immunity and Pathology in Mice Infected with Chlamydia muridarum

The p35 molecule is unique to interleukin-12 (IL-12), while p40 is shared by both IL-12 and IL-23. IL-12 promotes Th1 T cell responses, while IL-23 promotes Th17 T cell responses. The roles of IL-12p35- and IL-12p40-mediated responses in chlamydial infection were compared in mice following an intrav...

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Bibliographische Detailangaben
Hauptverfasser: Chen, Lili, Lei, Lei, Zhou, Zhou, He, Jie, Xu, Sha, Lu, Chunxue, Chen, Jianlin, Yang, Zhangsheng, Wu, Gangqiu, Yeh, I-Tien, Zhong, Guangming, Wu, Yimou
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Host Response and Inflammation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719579/
https://ncbi.nlm.nih.gov/pubmed/23753624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00161-13
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