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CD40 Mediates Maturation of Thymic Dendritic Cells Driven by Self-reactive CD4(+) Thymocytes and Supports Development of Natural Regulatory T Cells
Thymic dendritic cells (tDCs) play an important role in central tolerance by eliminating self-reactive thymocytes or differentiating them to regulatory T (Treg) cells. However, the molecular and cellular mechanisms underlying these functions are not completely understood. We found that mouse tDCs un...
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| Publicado no: | J Immunol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5809249/ https://ncbi.nlm.nih.gov/pubmed/29321275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700768 |
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