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CD40 Mediates Maturation of Thymic Dendritic Cells Driven by Self-reactive CD4(+) Thymocytes and Supports Development of Natural Regulatory T Cells

Thymic dendritic cells (tDCs) play an important role in central tolerance by eliminating self-reactive thymocytes or differentiating them to regulatory T (Treg) cells. However, the molecular and cellular mechanisms underlying these functions are not completely understood. We found that mouse tDCs un...

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Dades bibliogràfiques
Publicat a:J Immunol
Autors principals: Oh, Jaehak, Wu, Nan, Barczak, Andrea J., Barbeau, Rebecca, Erle, David J., Shin, Jeoung-Sook
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5809249/
https://ncbi.nlm.nih.gov/pubmed/29321275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700768
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