β1,4-Galactosyltransferase V activates Notch1 signaling in glioma stem-like cells and promotes their transdifferentiation into endothelial cells

Malignant glioblastoma multiforme is one of the most aggressive human cancers, with very low survival rates. Recent studies have reported that glioma stem-like cells transdifferentiate into endothelial cells, indicating a new mechanism for tumor angiogenesis and potentially providing new therapeutic...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Cui, Chunhong, Chen, Xiaoning, Liu, Ying, Cao, Benjin, Xing, Yang, Liu, Chanjuan, Yang, Fan, Li, Yinan, Yang, Tianxiao, Hua, Lingyang, Tian, Mi, Wei, Yuanyan, Gong, Ye, Jiang, Jianhai
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2018
Pynciau:
Signal Transduction
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808780/
https://ncbi.nlm.nih.gov/pubmed/29269413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000682
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