The Interaction between Cancer Stem Cell Marker CD133 and Src Protein Promotes Focal Adhesion Kinase (FAK) Phosphorylation and Cell Migration

CD133, a widely known cancer stem cell marker, has been proved to promote tumor metastasis. However, the mechanism by which CD133 regulates metastasis remains largely unknown. Here, we report that CD133 knockdown inhibits cancer cell migration, and CD133 overexpression promotes cell migration. CD133...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Biol Chem
Main Authors: Liu, Chanjuan, Li, Yinan, Xing, Yang, Cao, Benjin, Yang, Fan, Yang, Tianxiao, Ai, Zhilong, Wei, Yuanyan, Jiang, Jianhai
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2016
נושאים:
Signal Transduction
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4957040/
https://ncbi.nlm.nih.gov/pubmed/27226554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.712976
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