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Trans-SNARE complex dynamics and number determine nascent fusion pore properties

The fusion pore is the first crucial intermediate formed during exocytosis, yet little is known regarding the mechanisms that determine the size and kinetic properties of these transient structures(1). Here, we reduced the number of available SNAREs in neurons and observed changes in transmitter rel...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Bao, Huan, Das, Debasis, Courtney, Nicholas A., Jiang, Yihao, Briguglio, Joseph S., Lou, Xiaochu, Roston, Daniel, Cui, Qiang, Chanda, Baron, Chapman, Edwin R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808578/
https://ncbi.nlm.nih.gov/pubmed/29420480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature25481
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