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Synaptotagmin 1 clamps synaptic vesicle fusion in mammalian neurons independent of complexin
Synaptic vesicle (SV) exocytosis is mediated by SNARE proteins. Reconstituted SNAREs are constitutively active, so a major focus has been to identify fusion clamps that regulate their activity in synapses: the primary candidates are synaptotagmin (syt) 1 and complexin I/II. Syt1 is a Ca(2+) sensor f...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Nat Commun |
|---|---|
| Prif Awduron: | , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Nature Publishing Group UK
2019
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6733930/ https://ncbi.nlm.nih.gov/pubmed/31501440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12015-w |
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