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Trans-SNARE complex dynamics and number determine nascent fusion pore properties

The fusion pore is the first crucial intermediate formed during exocytosis, yet little is known regarding the mechanisms that determine the size and kinetic properties of these transient structures(1). Here, we reduced the number of available SNAREs in neurons and observed changes in transmitter rel...

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Bibliografiske detaljer
Udgivet i:Nature
Main Authors: Bao, Huan, Das, Debasis, Courtney, Nicholas A., Jiang, Yihao, Briguglio, Joseph S., Lou, Xiaochu, Roston, Daniel, Cui, Qiang, Chanda, Baron, Chapman, Edwin R.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808578/
https://ncbi.nlm.nih.gov/pubmed/29420480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature25481
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