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Trans-SNARE complex dynamics and number determine nascent fusion pore properties

The fusion pore is the first crucial intermediate formed during exocytosis, yet little is known regarding the mechanisms that determine the size and kinetic properties of these transient structures(1). Here, we reduced the number of available SNAREs in neurons and observed changes in transmitter rel...

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Detalles Bibliográficos
Publicado en:Nature
Main Authors: Bao, Huan, Das, Debasis, Courtney, Nicholas A., Jiang, Yihao, Briguglio, Joseph S., Lou, Xiaochu, Roston, Daniel, Cui, Qiang, Chanda, Baron, Chapman, Edwin R.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5808578/
https://ncbi.nlm.nih.gov/pubmed/29420480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature25481
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