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Directing T cell Fate: How Thymic Antigen Presenting Cells Coordinate Thymocyte Selection

The development of a self-tolerant and effective T cell receptor repertoire is dependent on interactions coordinated by various antigen presenting cells (APC) within the thymus. T cell receptor–self-peptide–MHC interactions are essential for determining T cell fate, however different cytokine and co...

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Bibliografiske detaljer
Udgivet i:Semin Cell Dev Biol
Main Authors: Breed, Elise R., Lee, S. Thera, Hogquist, Kristin A.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807247/
https://ncbi.nlm.nih.gov/pubmed/28800929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2017.07.045
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