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Intestinal CD8αα IELs derived from two distinct thymic precursors have staggered ontogeny
CD8αα intraepithelial lymphocytes (IELs) are abundant T cells that protect the gut epithelium. Their thymic precursors (IELps) include PD-1(+) type A and Tbet(+) type B populations, which differ in their antigen-receptor specificities. To better understand CD8αα IEL ontogeny, we performed “time-stam...
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| Foilsithe in: | J Exp Med |
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| Main Authors: | , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Rockefeller University Press
2020
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7398160/ https://ncbi.nlm.nih.gov/pubmed/32687575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20192336 |
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