Intestinal CD8αα IELs derived from two distinct thymic precursors have staggered ontogeny

CD8αα intraepithelial lymphocytes (IELs) are abundant T cells that protect the gut epithelium. Their thymic precursors (IELps) include PD-1(+) type A and Tbet(+) type B populations, which differ in their antigen-receptor specificities. To better understand CD8αα IEL ontogeny, we performed “time-stam...

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Detaylı Bibliyografya
Yayımlandı:J Exp Med
Asıl Yazarlar: Ruscher, Roland, Lee, S. Thera, Salgado, Oscar C., Breed, Elise R., Osum, Sara H., Hogquist, Kristin A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Rockefeller University Press 2020
Konular:
Brief Definitive Report
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7398160/
https://ncbi.nlm.nih.gov/pubmed/32687575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20192336
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