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Directing T cell Fate: How Thymic Antigen Presenting Cells Coordinate Thymocyte Selection
The development of a self-tolerant and effective T cell receptor repertoire is dependent on interactions coordinated by various antigen presenting cells (APC) within the thymus. T cell receptor–self-peptide–MHC interactions are essential for determining T cell fate, however different cytokine and co...
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| Veröffentlicht in: | Semin Cell Dev Biol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5807247/ https://ncbi.nlm.nih.gov/pubmed/28800929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2017.07.045 |
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