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Sinomenine potentiates P815 cell degranulation via upregulation of Ca(2+) mobilization through the Lyn/PLCγ/IP3R pathway

Mast cells are vital mediators of drug allergy and, therefore, studying the relationship between drug allergy and mast cells is essential. Sinomenine is the principal active component of Sinomenium acutum, which has anti-inflammatory and anti-immune effects, and is used to treat various rheumatoid di...

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Detalhes bibliográficos
Publicado no:Int J Immunopathol Pharmacol
Main Authors: Wang, Nan, Liu, Rui, Liu, Yanping, Zhang, Ruirui, He, Langchong
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5806832/
https://ncbi.nlm.nih.gov/pubmed/26714520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0394632015621768
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