p53 upregulates PLCε-IP3-Ca(2+) pathway and inhibits autophagy through its target gene Rap2B

The tumor suppressor p53 plays a pivotal role in numerous cellular responses as it regulates cell proliferation, metabolism, cellular growth, and autophagy. In order to identify novel p53 target genes, we utilized an unbiased microarray approach and identified Rap2B as a robust candidate, which belo...

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Enregistré dans:
Détails bibliographiques
Publié dans:Oncotarget
Auteurs principaux: Di, Jiehui, Tang, Juanjuan, Qian, Heya, Franklin, Derek A., Deisenroth, Chad, Itahana, Yoko, Zheng, Junnian, Zhang, Yanping
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2017
Sujets:
Priority Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630284/
https://ncbi.nlm.nih.gov/pubmed/29029384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18112
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