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STIM1 Knockout Enhances PDGF-Mediated Ca(2+) Signaling through Upregulation of the PDGFR–PLCγ–STIM2 Cascade
Platelet-derived growth factor (PDGF) has mitogenic and chemotactic effects on fibroblasts. An increase in intracellular Ca(2+) is one of the first events that occurs following the stimulation of PDGF receptors (PDGFRs). PDGF activates Ca(2+) elevation by activating the phospholipase C gamma (PLCγ)-...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6032054/ https://ncbi.nlm.nih.gov/pubmed/29912163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19061799 |
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