STIM1 Knockout Enhances PDGF-Mediated Ca2+ Signaling through Upregulation of the PDGFR–PLCγ–STIM2 Cascade

Platelet-derived growth factor (PDGF) has mitogenic and chemotactic effects on fibroblasts. An increase in intracellular Ca2+ is one of the first events that occurs following the stimulation of PDGF receptors (PDGFRs). PDGF activates Ca2+ elevation by activating the phospholipase C gamma (PLC&ga...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Tzu-Yu Huang, Yi-Hsin Lin, Heng-Ai Chang, Tzu-Ying Yeh, Ya-Han Chang, Yi-Fan Chen, Ying-Chi Chen, Chun-Chun Li, Wen-Tai Chiu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2018-06-01
Colecção:International Journal of Molecular Sciences
Assuntos:
Ca2+
STIM1
STIM2
SOCE
PDGF
PLCγ
Acesso em linha:http://www.mdpi.com/1422-0067/19/6/1799
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados