Comprehensive Dissection of PDGF-PDGFR Signaling Pathways in PDGFR Genetically Defined Cells

Despite the growing understanding of PDGF signaling, studies of PDGF function have encountered two major obstacles: the functional redundancy of PDGFRα and PDGFRβ in vitro and their distinct roles in vivo. Here we used wild-type mouse embryonic fibroblasts (MEF), MEF null for either PDGFRα, β, or bo...

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Autors principals: Wu, Erxi, Palmer, Nathan, Tian, Ze, Moseman, Annie P., Galdzicki, Michal, Wang, Xuetao, Berger, Bonnie, Zhang, Hongbing, Kohane, Isaac S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2008
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582946/
https://ncbi.nlm.nih.gov/pubmed/19030102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003794
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