Toxoplasma gondii inhibits mast cell degranulation by suppressing phospholipase Cγ-mediated Ca(2+) mobilization

Toxoplasma gondii is well-known to subvert normal immune responses, however, mechanisms are incompletely understood. In particular, its capacity to alter receptor-activated Ca(2+)-mediated signaling processes has not been well-characterized. In initial experiments, we found evidence that T. gondii i...

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Autors principals: Smith, Norah L., Abi Abdallah, Delbert S., Butcher, Barbara A., Denkers, Eric Y., Baird, Barbara, Holowka, David
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2013
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701878/
https://ncbi.nlm.nih.gov/pubmed/23847603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2013.00179
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