טוען...
Turning the tables on cytomegalovirus: targeting viral Fc receptors by CARs containing mutated CH2–CH3 IgG spacer domains
BACKGROUND: During infection with human cytomegalovirus (HCMV) several viral proteins occur on cell surfaces in high quantity. We thus pursue an HLA-independent approach for immunotherapy of HCMV using chimeric antigen receptors (CARs) and bispecific BiTE(®) antibody constructs. In this context, HCM...
שמור ב:
| הוצא לאור ב: | J Transl Med |
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| Main Authors: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
BioMed Central
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5804023/ https://ncbi.nlm.nih.gov/pubmed/29422056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1394-x |
| תגים: |
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