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Colistin-indiced apoptosis of neuroblastoma-2a cells involves the generation of reactive oxygen species, mitochondria dysfunction and autophagy

Neurotoxicity remains a poorly characterized an adverse effect associated with colistin therapy. The aim of the present study was to investigate the mechanism of colistin-induced neurotoxicity using the mouse neuroblastoma-2a (N2a) cell line. Colistin induced apoptotic neuronal cell death in a dose...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Dai, Chongshan, Tang, Shusheng, Velkov, Tony, Xiao, Xilong
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801544/
https://ncbi.nlm.nih.gov/pubmed/26316077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-015-9396-7
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