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Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination

Antibody Fab fragments have been exploited with significant success to facilitate the structure determination of challenging macromolecules as crystallization chaperones and as molecular fiducial marks for single particle cryo-EM approaches. However, the inherent flexibility of the “elbow” regions,...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Mol Biol
Päätekijät: Bailey, Lucas J., Sheehy, Kimberly M., Dominik, Pawel K., Liang, Vinson, Rui, Huan, Clark, Michael, Jaskolowski, Mateusz, Kim, Yejoon, Deneka, Dawid, Tang, Wei-Jen, Kossiakoff, Anthony A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800945/
https://ncbi.nlm.nih.gov/pubmed/29273204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.12.012
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