Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination

Antibody Fab fragments have been exploited with significant success to facilitate the structure determination of challenging macromolecules as crystallization chaperones and as molecular fiducial marks for single particle cryo-EM approaches. However, the inherent flexibility of the “elbow” regions,...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Mol Biol
Egile Nagusiak: Bailey, Lucas J., Sheehy, Kimberly M., Dominik, Pawel K., Liang, Vinson, Rui, Huan, Clark, Michael, Jaskolowski, Mateusz, Kim, Yejoon, Deneka, Dawid, Tang, Wei-Jen, Kossiakoff, Anthony A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800945/
https://ncbi.nlm.nih.gov/pubmed/29273204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.12.012
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