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Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination
Antibody Fab fragments have been exploited with significant success to facilitate the structure determination of challenging macromolecules as crystallization chaperones and as molecular fiducial marks for single particle cryo-EM approaches. However, the inherent flexibility of the “elbow” regions,...
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| Pubblicato in: | J Mol Biol |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5800945/ https://ncbi.nlm.nih.gov/pubmed/29273204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.12.012 |
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