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Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination
Antibody Fab fragments have been exploited with significant success to facilitate the structure determination of challenging macromolecules as crystallization chaperones and as molecular fiducial marks for single particle cryo-EM approaches. However, the inherent flexibility of the “elbow” regions,...
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| Publicado en: | J Mol Biol |
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| Autores principales: | , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5800945/ https://ncbi.nlm.nih.gov/pubmed/29273204 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.12.012 |
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