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Applications for an engineered Protein-G variant with a pH controllable affinity to antibody fragments

Immunoglobulin binding proteins (IBPs) are broadly used as reagents for the purification and detection of antibodies. Among the IBPs, the most widely used are Protein-A and Protein-G. The C2 domain of Protein-G from Streptococcus is a multi-specific protein domain; it possesses a high affinity (K(D)...

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Detalhes bibliográficos
Publicado no:J Immunol Methods
Main Authors: Bailey, Lucas J., Sheehy, Kimberly M., Hoey, Robert J., Schaefer, Zachary P., Ura, Marcin, Kossiakoff, Anthony A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4257880/
https://ncbi.nlm.nih.gov/pubmed/25450256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2014.10.003
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