Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination

Antibody Fab fragments have been exploited with significant success to facilitate the structure determination of challenging macromolecules as crystallization chaperones and as molecular fiducial marks for single particle cryo-EM approaches. However, the inherent flexibility of the “elbow” regions,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Mol Biol
Prif Awduron: Bailey, Lucas J., Sheehy, Kimberly M., Dominik, Pawel K., Liang, Vinson, Rui, Huan, Clark, Michael, Jaskolowski, Mateusz, Kim, Yejoon, Deneka, Dawid, Tang, Wei-Jen, Kossiakoff, Anthony A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800945/
https://ncbi.nlm.nih.gov/pubmed/29273204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.12.012
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