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Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination

Antibody Fab fragments have been exploited with significant success to facilitate the structure determination of challenging macromolecules as crystallization chaperones and as molecular fiducial marks for single particle cryo-EM approaches. However, the inherent flexibility of the “elbow” regions,...

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Bibliografski detalji
Izdano u:J Mol Biol
Glavni autori: Bailey, Lucas J., Sheehy, Kimberly M., Dominik, Pawel K., Liang, Vinson, Rui, Huan, Clark, Michael, Jaskolowski, Mateusz, Kim, Yejoon, Deneka, Dawid, Tang, Wei-Jen, Kossiakoff, Anthony A.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800945/
https://ncbi.nlm.nih.gov/pubmed/29273204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.12.012
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