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The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab

The vast majority of platforms for the detection of viral or bacterial antigens rely on immunoassays, typically ELISA or sandwich ELISA, that are contingent on the availability of suitable monoclonal antibodies (mAbs). This is a major bottleneck, since the generation and production of mAbs is time-c...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr D Struct Biol
Main Authors: Radwańska, Malwina J., Jaskółowski, Mateusz, Davydova, Elena, Derewenda, Urszula, Miyake, Tsuyoshi, Engel, Daniel A., Kossiakoff, Anthony A., Derewenda, Zygmunt S.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038385/
https://ncbi.nlm.nih.gov/pubmed/29968677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798318007878
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