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The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab

The vast majority of platforms for the detection of viral or bacterial antigens rely on immunoassays, typically ELISA or sandwich ELISA, that are contingent on the availability of suitable monoclonal antibodies (mAbs). This is a major bottleneck, since the generation and production of mAbs is time-c...

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Vydáno v:Acta Crystallogr D Struct Biol
Hlavní autoři: Radwańska, Malwina J., Jaskółowski, Mateusz, Davydova, Elena, Derewenda, Urszula, Miyake, Tsuyoshi, Engel, Daniel A., Kossiakoff, Anthony A., Derewenda, Zygmunt S.
Médium: Artigo
Jazyk:Inglês
Vydáno: International Union of Crystallography 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038385/
https://ncbi.nlm.nih.gov/pubmed/29968677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798318007878
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