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The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab

The vast majority of platforms for the detection of viral or bacterial antigens rely on immunoassays, typically ELISA or sandwich ELISA, that are contingent on the availability of suitable monoclonal antibodies (mAbs). This is a major bottleneck, since the generation and production of mAbs is time-c...

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Détails bibliographiques
Publié dans:Acta Crystallogr D Struct Biol
Auteurs principaux: Radwańska, Malwina J., Jaskółowski, Mateusz, Davydova, Elena, Derewenda, Urszula, Miyake, Tsuyoshi, Engel, Daniel A., Kossiakoff, Anthony A., Derewenda, Zygmunt S.
Format: Artigo
Langue:Inglês
Publié: International Union of Crystallography 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6038385/
https://ncbi.nlm.nih.gov/pubmed/29968677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798318007878
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