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High αv Integrin Level of Cancer Cells Is Associated with Development of Brain Metastasis in Athymic Rats

BACKGROUND/AIM: Brain metastases commonly occur in patients with malignant skin, lung and breast cancers resulting in high morbidity and poor prognosis. Integrins containing an αv subunit are cell adhesion proteins that contribute to cancer cell migration and cancer progression. We hypothesized that...

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Bibliographic Details
Published in:Anticancer Res
Main Authors: WU, YINGJEN JEFFREY, PAGEL, MICHAEL A., MULDOON, LESLIE L., FU, RONGWEI, NEUWELT, EDWARD A.
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5800856/
https://ncbi.nlm.nih.gov/pubmed/28739685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/anticanres.11788
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