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Vascular endothelial growth factor blockade alters magnetic resonance imaging biomarkers of vascular function and decreases barrier permeability in a rat model of lung cancer brain metastasis
BACKGROUND: Blockade of vascular endothelial growth factor (VEGF) to promote vascular normalization and inhibit angiogenesis has been proposed for the treatment of brain metastases; however, vascular normalization has not been well-characterized in this disease. We investigated the effect of treatme...
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Udgivet i: | Fluids Barriers CNS |
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Main Authors: | , , , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
BioMed Central
2015
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4429592/ https://ncbi.nlm.nih.gov/pubmed/25879723 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-8118-12-5 |
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