Vascular endothelial growth factor blockade alters magnetic resonance imaging biomarkers of vascular function and decreases barrier permeability in a rat model of lung cancer brain metastasis

BACKGROUND: Blockade of vascular endothelial growth factor (VEGF) to promote vascular normalization and inhibit angiogenesis has been proposed for the treatment of brain metastases; however, vascular normalization has not been well-characterized in this disease. We investigated the effect of treatme...

Full description

Saved in:
Bibliographic Details
Published in:Fluids Barriers CNS
Main Authors: Pishko, Gregory L, Muldoon, Leslie L, Pagel, Michael A, Schwartz, Daniel L, Neuwelt, Edward A
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429592/
https://ncbi.nlm.nih.gov/pubmed/25879723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-8118-12-5
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items