Dynamic magnetic resonance imaging assessment of vascular targeting agent effects in rat intracerebral tumor models

We used dynamic MRI to evaluate the effects of monoclonal antibodies targeting brain tumor vasculature. Female athymic rats with intracerebral human tumor xenografts were untreated or treated with intetumumab, targeting α(V)-integrins, or bevacizumab, targeting vascular endothelial growth factor (n...

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Главные авторы: Muldoon, Leslie L., Gahramanov, Seymur, Li, Xin, Marshall, Deborah J., Kraemer, Dale F., Neuwelt, Edward A.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2011
Предметы:
Basic and Translational Investigations
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018910/
https://ncbi.nlm.nih.gov/pubmed/21123368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq150
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