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Targeting α(V)-integrins decreased metastasis and increased survival in a nude rat breast cancer brain metastasis model
Brain metastases commonly occur in patients with breast, lung and melanoma systemic cancers. The anti-α(V) integrin monoclonal antibody intetumumab binds cell surface proteins important for adhesion, invasion and angiogenesis in the metastatic cascade. The objective of this study was to investigate...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3726254/ https://ncbi.nlm.nih.gov/pubmed/22842979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-012-0942-0 |
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