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Inhibiting α(v) Integrins Decreases the Malignant Characteristics of Medulloblastoma

OBJECT: Hypoxia induces an aggressive phenotype in some brain tumors in part due to hypoxia inducible factor 1α (HIF-1α) and integrin expression. The importance of hypoxia in medulloblastoma is unclear and the interaction of HIF-1α and c-Myc in medulloblastoma has not been explored. The objective of...

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Detalhes bibliográficos
Main Authors: Thompson, Eric M., Whitney, Nathanial L., Wu, Y. Jeffery, Neuwelt, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3709582/
https://ncbi.nlm.nih.gov/pubmed/23082872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2012.9.PEDS12268
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