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Interactions between αv-Integrin and HER2 and Their Role in the Invasive Phenotype of Breast Cancer Cells In Vitro and in Rat Brain

BACKGROUND: We tested the hypothesis that αv-integrin and the human epidermal growth factor receptor type 2 (HER2) interact with each other in brain trophic metastatic breast cancer cells and influence their invasive phenotype. METHODS: Clones of MDA-MB231BR human breast cancer cells with stable kno...

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Veröffentlicht in:PLoS One
Hauptverfasser: Lal, Sangeet, Kersch, Cymon, Beeson, Kathleen A., Wu, Y. Jeffrey, Muldoon, Leslie L., Neuwelt, Edward A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4519046/
https://ncbi.nlm.nih.gov/pubmed/26222911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0131842
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