EXTH-39. EFFICACY OF THE ANTIBODY-DRUG CONJUGATE ABT-414 IN BRAIN TUMOR MODELS

Brain tumor treatment is limited by a lack of effective therapies and inadequate drug delivery across the blood-brain barrier (BBB). The antibody-drug conjugate (ADC) ABT-414 (AbbVie Pharmaceuticals) couples the toxin monomethyl auristatin F to a humanized monoclonal antibody targeting overexpressed...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Muldoon, Leslie, McConnell, Heather, Kersch, Cymon, Neuwelt, Edward
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
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Abstracts
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5692295/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.331
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