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EXTH-39. EFFICACY OF THE ANTIBODY-DRUG CONJUGATE ABT-414 IN BRAIN TUMOR MODELS
Brain tumor treatment is limited by a lack of effective therapies and inadequate drug delivery across the blood-brain barrier (BBB). The antibody-drug conjugate (ADC) ABT-414 (AbbVie Pharmaceuticals) couples the toxin monomethyl auristatin F to a humanized monoclonal antibody targeting overexpressed...
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| Pubblicato in: | Neuro Oncol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692295/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.331 |
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