Dynamic magnetic resonance imaging assessment of vascular targeting agent effects in rat intracerebral tumor models

We used dynamic MRI to evaluate the effects of monoclonal antibodies targeting brain tumor vasculature. Female athymic rats with intracerebral human tumor xenografts were untreated or treated with intetumumab, targeting α(V)-integrins, or bevacizumab, targeting vascular endothelial growth factor (n...

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Bibliographische Detailangaben
Hauptverfasser: Muldoon, Leslie L., Gahramanov, Seymur, Li, Xin, Marshall, Deborah J., Kraemer, Dale F., Neuwelt, Edward A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2011
Schlagworte:
Basic and Translational Investigations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018910/
https://ncbi.nlm.nih.gov/pubmed/21123368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noq150
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